Detalhe da pesquisa
1.
Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.
Cell
; 175(5): 1244-1258.e26, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30454645
2.
Dose, schedule, safety, and efficacy of guadecitabine in relapsed or refractory acute myeloid leukemia.
Cancer
; 124(2): 325-334, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29211308
3.
Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study.
Lancet Oncol
; 16(9): 1099-1110, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26296954
4.
Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.
Gastroenterology
; 146(2): 530-38.e5, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24211491
5.
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer.
Genome Res
; 20(10): 1369-82, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20716667
6.
A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clin Cancer Res
; 29(11): 2052-2065, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928921
7.
Tumor-associated methylation of the putative tumor suppressor AJAP1 gene and association between decreased AJAP1 expression and shorter survival in patients with glioma.
Chin J Cancer
; 30(4): 247-53, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21439246
8.
Sensitive and specific detection of early gastric cancer with DNA methylation analysis of gastric washes.
Gastroenterology
; 136(7): 2149-58, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19375421
9.
Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.
Blood
; 112(4): 1366-73, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18523155
10.
Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia.
Clin Epigenetics
; 11(1): 106, 2019 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31331399
11.
Whole-Organ Genomic Characterization of Mucosal Field Effects Initiating Bladder Carcinogenesis.
Cell Rep
; 26(8): 2241-2256.e4, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784602
12.
Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.
Lab Invest
; 88(7): 694-721, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18458673
13.
Age-related DNA methylation changes in normal human prostate tissues.
Clin Cancer Res
; 13(13): 3796-802, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17606710
14.
Silencing of bidirectional promoters by DNA methylation in tumorigenesis.
Cancer Res
; 66(10): 5077-84, 2006 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16707430
15.
Transcriptional Selectivity of Epigenetic Therapy in Cancer.
Cancer Res
; 77(2): 470-481, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27879268
16.
Differentially methylated genes and androgen receptor re-expression in small cell prostate carcinomas.
Epigenetics
; 11(3): 184-93, 2016 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26890396
17.
Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.
Cancer Res
; 76(6): 1494-505, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719529
18.
Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
Cancer Res
; 74(5): 1311-8, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24385213
19.
Examination of whole blood DNA methylation as a potential risk marker for gastric cancer.
Cancer Prev Res (Phila)
; 6(10): 1093-100, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943784
20.
Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers.
Cancer Discov
; 3(7): 770-81, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23619168